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Description
This landmark study led to FDA approval expansion in March 2024 for Wegovy (semaglutide 2.4 mg) to reduce the risk of cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke in adults with cardiovascular disease and either obesity or overweight

10.1016/j.molmet.2019.09.010 45 MuraliS.AradhyamG

They arent

Nonetheless, the receptor side chains within the pocket exhibit similar rotamers
